Showing entry for DNA-directed primase/polymerase protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019695
Protein NameDNA-directed primase/polymerase protein
Uniport IdQ96LW4
GenePRIMPOL
Gene Id201973
DomainDNA_primase_S
Pfam PF01896  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042276 error-prone translesion synthesis
Biological Process GO:0043504 mitochondrial DNA repair
Biological Process GO:0006264 mitochondrial DNA replication
Biological Process GO:0031297 replication fork processing
Biological Process GO:0009411 response to UV
Biological Process GO:0062176 R-loop disassembly
Biological Process GO:0019985 translesion synthesis
molecular function GO:0003682 chromatin binding
molecular function GO:0003887 DNA-directed DNA polymerase activity
molecular function GO:0003896 DNA primase activity
molecular function GO:0030145 manganese ion binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005634 nucleus
cellular component GO:0005657 replication fork
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0027092 BXGD001971 Myopia Eye Diseases
C0162674 BXGD003973 Chronic progressive external ophthalmoplegia Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0234632 BXGD004691 Reduced visual acuity Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0271183 BXGD006169 Severe myopia Eye Diseases
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C3809464 BXGD019590 MYOPIA 22, AUTOSOMAL DOMINANT
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein