Showing entry for NACHT, LRR and PYD domains-containing protein 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019697
Protein NameNACHT, LRR and PYD domains-containing protein 4
Uniport IdQ96MN2
GeneNLRP4
Gene Id147945
DomainLRR_6; NACHT; NLRC4_HD2; NOD2_WH; PYRIN
Pfam PF13516   PF05729   PF17776   PF17779   PF02758  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006954 inflammatory response
Biological Process GO:0032479 regulation of type I interferon production
molecular function GO:0005524 ATP binding
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs
R-HSA-1606341 IRF3 mediated activation of type 1 IFN
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-1834941 STING mediated induction of host immune responses
R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA
R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA
R-HSA-3270619 IRF3-mediated induction of type I IFN
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0042075 BXGD002955 Urologic Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0201512 BXGD004048 Thyroglobulin antibody measurement
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2145472 BXGD016931 Urothelial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2350019 BXGD017066 Solitary Pulmonary Nodule Respiratory Tract Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein