Showing entry for N-acetylmuramoyl-L-alanine amidase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019706
Protein NameN-acetylmuramoyl-L-alanine amidase
Uniport IdQ96PD5
GenePGLYRP2
Gene Id114770
DomainAmidase_2
Pfam PF01510  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019730 antimicrobial humoral response
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0016045 detection of bacterium
Biological Process GO:0044117 growth of symbiont in host
Biological Process GO:0045087 innate immune response
Biological Process GO:0032689 negative regulation of interferon-gamma production
Biological Process GO:0032827 negative regulation of natural killer cell differentiation involved in immune response
Biological Process GO:0001519 peptide amidation
Biological Process GO:0009253 peptidoglycan catabolic process
Biological Process GO:0050727 regulation of inflammatory response
molecular function GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
molecular function GO:0042834 peptidoglycan binding
molecular function GO:0016019 peptidoglycan immune receptor activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6803157 Antimicrobial peptides
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004623 BXGD000282 Bacterial Infections Infections
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2985280 BXGD018223 Blood Protein Measurement
C4529962 BXGD023178 Fatty Liver Disease
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002616 Copper 63.55
BXGC0002682 Zinc 65.41
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein