Showing entry for Protein orai-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019742
Protein NameProtein orai-2
Uniport IdQ96SN7
GeneORAI2
Gene Id80228
DomainOrai-1
Pfam PF07856  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002115 store-operated calcium entry
molecular function GO:0015279 store-operated calcium channel activity
cellular component GO:0030426 growth cone
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-1280218 Adaptive Immune System
R-HSA-139853 Elevation of cytosolic Ca2+ levels
R-HSA-168256 Immune System
R-HSA-397014 Muscle contraction
R-HSA-418346 Platelet homeostasis
R-HSA-418360 Platelet calcium homeostasis
R-HSA-5576891 Cardiac conduction
R-HSA-5578775 Ion homeostasis
R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
R-HSA-983705 Signaling by the B Cell Receptor (BCR)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0007499 Boric acid (H3BO3) 61.83
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein