protein

Showing entry for Voltage-dependent L-type calcium channel subunit alpha-1D

General Target Information
BXGT Id	BXGT019912
Protein Name	Voltage-dependent L-type calcium channel subunit alpha-1D
Uniport Id	Q99246
Gene	Cacna1d
Gene Id	12289
Domain	CAC1F_C; Ca_chan_IQ; GPHH; Ion_trans
Pfam	PF08763 PF16885 PF16905 PF00520
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process	GO:0070509	calcium ion import
Biological Process	GO:0070588	calcium ion transmembrane transport
Biological Process	GO:0006816	calcium ion transport
Biological Process	GO:0019722	calcium-mediated signaling
Biological Process	GO:0061337	cardiac conduction
Biological Process	GO:0086002	cardiac muscle cell action potential involved in contraction
Biological Process	GO:0070838	divalent metal ion transport
Biological Process	GO:0086046	membrane depolarization during SA node cell action potential
Biological Process	GO:0045762	positive regulation of adenylate cyclase activity
Biological Process	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
Biological Process	GO:0051928	positive regulation of calcium ion transport
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization
Biological Process	GO:0051924	regulation of calcium ion transport
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport
Biological Process	GO:1901016	regulation of potassium ion transmembrane transporter activity
Biological Process	GO:0007605	sensory perception of sound
molecular function	GO:0051393	alpha-actinin binding
molecular function	GO:0030506	ankyrin binding
molecular function	GO:0005262	calcium channel activity
molecular function	GO:0008331	high voltage-gated calcium channel activity
molecular function	GO:0046872	metal ion binding
molecular function	GO:0030165	PDZ domain binding
molecular function	GO:0005245	voltage-gated calcium channel activity
molecular function	GO:0099635	voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
molecular function	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential
cellular component	GO:0016324	apical plasma membrane
cellular component	GO:0009986	cell surface
cellular component	GO:0098683	cochlear hair cell ribbon synapse
cellular component	GO:0005737	cytoplasm
cellular component	GO:0030425	dendrite
cellular component	GO:0032590	dendrite membrane
cellular component	GO:0005887	integral component of plasma membrane
cellular component	GO:0099059	integral component of presynaptic active zone membrane
cellular component	GO:1990454	L-type voltage-gated calcium channel complex
cellular component	GO:0043025	neuronal cell body
cellular component	GO:0005634	nucleus
cellular component	GO:0005886	plasma membrane
cellular component	GO:0042383	sarcolemma
cellular component	GO:0005891	voltage-gated calcium channel complex
cellular component	GO:0030018	Z disc

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0024988	Nifedipine		346.12

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}