Showing entry for M-phase phosphoprotein 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019932
Protein NameM-phase phosphoprotein 8
Uniport IdQ99549
GeneMPHOSPH8
Gene Id54737
DomainAnk_2; Chromo
Pfam PF12796   PF00385  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045814 negative regulation of gene expression, epigenetic
Biological Process GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly
Biological Process GO:0044030 regulation of DNA methylation
molecular function GO:0003682 chromatin binding
molecular function GO:0035064 methylated histone binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0000792 heterochromatin
cellular component GO:0005720 nuclear heterochromatin
cellular component GO:0000788 nuclear nucleosome
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000099 3,4-Dihydroxyphenylacetic acid 168.15
BXGC0000286 L-DOPA 197.19
BXGC0000430 Gossypol 518.55
BXGC0000530 Hydroquinone 110.11
BXGC0000895 5-Hydroxyindole-3-acetic acid 191.18
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001238 3-Methoxy-4-hydroxyphenylacetic acid 182.17
BXGC0001623 L-Tryptophan 204.23
BXGC0001767 (E)-Resveratrol 228.25
BXGC0001940 Daphnetin 178.14
BXGC0002018 Morin 302.24
BXGC0002071 Apigenin 270.24
BXGC0002906 Caffeic acid ester 284.31
BXGC0002916 Melatonin 232.28
BXGC0003456 1,4-Benzoquinone 108.09
BXGC0003610 5-Hydroxy-L-tryptophan 220.22
BXGC0004548 4-(beta-Methylaminoethyl)catechol 167.21
BXGC0004763 Octopamine 153.18
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0005871 Dopamine 153.18
BXGC0006306 Myricetin 318.24
BXGC0006389 Rotenone 394.42
BXGC0007029 Emodin 270.24
BXGC0008184 Phloretin 274.27
BXGC0008707 Isoliquiritigenin 256.25
BXGC0009649 Dihydrocapsaicin 307.43
BXGC0014695 Loratadine 382.14
BXGC0016470 Camptothecin 348.11
BXGC0016681 Hispidin 246.05
BXGC0016886 Papaverine Hydrochloride 339.15
BXGC0016973 Guvacine Hydrochloride 127.06
BXGC0018736 Benzamide 121.05
BXGC0019164 Raloxifene 473.17
BXGC0021478 Lipoic Acid 206.04
BXGC0024988 Nifedipine 346.12
BXGC0028001 Beta-Lapachone 242.09
BXGC0030685 Physostigmine 275.16
BXGC0031384 Epinephrine 183.09
BXGC0034256 Rottlerin 516.18
BXGC0034379 Tetraethylammonium Chloride 130.16
BXGC0036441 Quisqualate 189.04
BXGC0042091 Dequalinium 456.33
BXGC0042870 Piceatannol 244.07
BXGC0043126 Nicardipine 479.21
BXGC0045252 Sc-560 352.06
BXGC0045254 Sb-202190 331.11
BXGC0045812 Trifluoperazine 407.16
BXGC0048661 Nicardipine Hydrochloride 479.21
BXGC0052374 Reserpine 608.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein