Showing entry for Cerebral cavernous malformations 2 protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020123
Protein NameCerebral cavernous malformations 2 protein
Uniport IdQ9BSQ5
GeneCCM2
Gene Id83605
DomainCCM2_C
Pfam PF16545  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060837 blood vessel endothelial cell differentiation
Biological Process GO:0045216 cell-cell junction organization
Biological Process GO:0001885 endothelial cell development
Biological Process GO:0061154 endothelial tube morphogenesis
Biological Process GO:0048839 inner ear development
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0060039 pericardium development
Biological Process GO:0051403 stress-activated MAPK cascade
Biological Process GO:0001570 vasculogenesis
Biological Process GO:0048845 venous blood vessel morphogenesis
cellular component GO:0005737 cytoplasm
cellular component GO:0005739 mitochondrion
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0018681 BXGD001214 Headache Pathological Conditions, Signs and Symptoms
C0018920 BXGD001246 Hemangioma, Cavernous Neoplasms; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027858 BXGD002051 Neuroma Neoplasms
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039446 BXGD002811 Telangiectasis Cardiovascular Diseases
C0151740 BXGD003468 Intracranial Hypertension Nervous System Diseases
C0162819 BXGD003984 Skin Diseases, Vascular Skin and Connective Tissue Diseases
C0241224 BXGD005087 Spinal cord lesion Nervous System Diseases
C0265950 BXGD005588 Venous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0346010 BXGD007762 Multiple fibrofolliculomas Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0346390 BXGD007820 Hemangioma of choroid Neoplasms; Cardiovascular Diseases
C0478007 BXGD009010 Other malformations of cerebral vessels
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0730304 BXGD009951 Cavernous hemangioma of retina Neoplasms; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0747845 BXGD010184 early pregnancy
C0752160 BXGD010681 Hemangioma, Cavernous, Central Nervous System Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0752161 BXGD010682 Cavernous Hemangioma, Extracerebral Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0752164 BXGD010683 Cavernous Hemangioma, Intracerebral Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C1140710 BXGD011719 Cerebral Cavernous Hemangioma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C1334953 BXGD012746 Neuroblastic tumors Neoplasms
C1366911 BXGD012881 Cerebral Cavernous Malformations 1
C1402315 BXGD013017 Vascular lesions
C1611743 BXGD013456 Familial (FPAH)
C1838993 BXGD014351 Episodic vomiting Pathological Conditions, Signs and Symptoms
C1864040 BXGD016210 Cerebral Cavernous Malformations 3 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms
C1864041 BXGD016211 CEREBRAL CAVERNOUS MALFORMATIONS 2 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases; Behavior and Behavior Mechanisms
C1956260 BXGD016625 Cavernous Angioma, Central Nervous System Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C1956261 BXGD016626 Cerebral Venous Angioma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1959589 BXGD016641 Angioma, Cavernous Neoplasms; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C2910157 BXGD017863 Nonruptured congenital cerebral aneurysm
C2910158 BXGD017864 Congenital malformation of cerebral vessels NOS
C2919945 BXGD017882 Cavernous Hemangioma of Brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C2931263 BXGD017992 Familial cerebral cavernous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C2937220 BXGD018154 Congenital abnormality of vein Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2937358 BXGD018159 Cerebral Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C4022747 BXGD020978 Focal T2 hypointense brainstem lesion
C4022748 BXGD020979 Focal T2 hyperintense brainstem lesion
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4747394 BXGD023970 CAPILLARY MALFORMATION-ARTERIOVENOUS MALFORMATION 1
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0038991 Selenomethionine 197
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein