Showing entry for Dehydrogenase/reductase SDR family member 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020129
Protein NameDehydrogenase/reductase SDR family member 4
Uniport IdQ9BTZ2
GeneDHRS4
Gene Id10901
Domainadh_short_C2
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00830 Retinol metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
4. Cellular Processes 4.1 Transport and catabolism hsa04146 Peroxisome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006066 alcohol metabolic process
Biological Process GO:0042180 cellular ketone metabolic process
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0006625 protein targeting to peroxisome
Biological Process GO:0008202 steroid metabolic process
molecular function GO:0000253 3-keto sterol reductase activity
molecular function GO:0004090 carbonyl reductase (NADPH) activity
molecular function GO:0042802 identical protein binding
molecular function GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
cellular component GO:0005829 cytosol
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0005634 nucleus
cellular component GO:0005782 peroxisomal matrix
cellular component GO:0005778 peroxisomal membrane
cellular component GO:0005777 peroxisome
molecular function GO:0018455 alcohol dehydrogenase NAD(P)+ activity
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-5362517 Signaling by Retinoic Acid
R-HSA-5365859 RA biosynthesis pathway
R-HSA-9006931 Signaling by Nuclear Receptors
R-HSA-9033241 Peroxisomal protein import
R-HSA-9033241 Peroxisomal protein import
R-HSA-9609507 Protein localization
R-HSA-9609507 Protein localization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1269955 BXGD012005 Tumor Cell Invasion
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0047568 Retinol 286.23
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein