Showing entry for Collectin-11


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020153
Protein NameCollectin-11
Uniport IdQ9BWP8
GeneCOLEC11
Gene Id78989
DomainCollagen; Lectin_C
Pfam PF01391   PF00059  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019730 antimicrobial humoral response
Biological Process GO:0006956 complement activation
Biological Process GO:0001867 complement activation, lectin pathway
Biological Process GO:0032502 developmental process
Biological Process GO:0097194 execution phase of apoptosis
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0006898 receptor-mediated endocytosis
molecular function GO:0120153 calcium-dependent carbohydrate binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0003677 DNA binding
molecular function GO:0042806 fucose binding
molecular function GO:0005537 mannose binding
molecular function GO:0070492 oligosaccharide binding
cellular component GO:0005581 collagen trimer
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
R-HSA-166658 Complement cascade
R-HSA-166662 Lectin pathway of complement activation
R-HSA-166663 Initial triggering of complement
R-HSA-166786 Creation of C4 and C2 activators
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors
R-HSA-3000480 Scavenging by Class A Receptors
R-HSA-5653656 Vesicle-mediated transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004623 BXGD000282 Bacterial Infections Infections
C0005744 BXGD000330 Blepharophimosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0008924 BXGD000574 Cleft upper lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0012739 BXGD000786 Disseminated Intravascular Coagulation Hemic and Lymphatic Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0022283 BXGD001533 Incontinentia Pigmenti Achromians Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024003 BXGD001726 Lordosis Musculoskeletal Diseases
C0032269 BXGD002342 Pneumococcal Infections Infections
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0033626 BXGD002412 Protein Deficiency Nutritional and Metabolic Diseases
C0036305 BXGD002593 Schamberg Disease Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0036323 BXGD002595 Schistosomiasis Infections
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0040485 BXGD002871 Torticollis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041234 BXGD002901 Chagas Disease Infections
C0041296 BXGD002903 Tuberculosis Infections
C0042769 BXGD002999 Virus Diseases Infections
C0080174 BXGD003106 Spina Bifida Occulta Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0086437 BXGD003282 Joint laxity Musculoskeletal Diseases
C0158761 BXGD003905 Radioulnar Synostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221766 BXGD004478 Diastasis recti Musculoskeletal Diseases; Wounds and Injuries
C0239234 BXGD004974 Low set ears
C0240414 BXGD005035 Hypoplasia of muscle
C0242966 BXGD005201 Systemic Inflammatory Response Syndrome Pathological Conditions, Signs and Symptoms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0266011 BXGD005605 Accessory nipple Skin and Connective Tissue Diseases
C0337428 BXGD007155 Fibrinogen assay
C0376634 BXGD008006 Craniofacial Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0376705 BXGD008009 Viral Load result
C0423110 BXGD008471 Downward slant of palpebral fissure
C0423113 BXGD008473 Telecanthus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0431663 BXGD008700 Bilateral Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0549567 BXGD009387 Pigmentation Disorders Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0557874 BXGD009444 Global developmental delay
C0796032 BXGD010784 Malpuech facial clefting syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Mental Disorders; Cardiovascular Diseases
C0796059 BXGD010790 Oculopalatoskeletal syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases
C0796279 BXGD010830 Carnevale syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Male Urogenital Diseases; Nervous System Diseases; Endocrine System Diseases
C1303003 BXGD012318 Epicanthus inversus
C1306503 BXGD012363 Congenital exomphalos Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1704430 BXGD013562 Urinary Schistosomiasis Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C1834129 BXGD013957 Abnormal vertebral morphology
C1836230 BXGD014099 HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
C1836231 BXGD014100 HIV-1, RESISTANCE TO
C1836232 BXGD014101 ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
C1836233 BXGD014102 AIDS, PROGRESSION TO
C1849089 BXGD015004 Broad forehead
C1849367 BXGD015046 Nasal bridge wide
C1849955 BXGD015094 Limited elbow movement
C1854111 BXGD015381 Broad philtrum
C1854113 BXGD015382 Prominent nasal bridge
C1859717 BXGD015924 Depressed nasal tip
C1859778 BXGD015931 Postnatal growth retardation
C1861331 BXGD016034 Limited pronation/supination of forearm
C1866195 BXGD016385 Downturned corners of mouth
C1868571 BXGD016508 Highly arched eyebrow
C1969372 BXGD016775 Tubulointerstitial fibrosis
C2697767 BXGD017437 Interleukin 19 Measurement
C2749369 BXGD017619 Prominence of the premaxilla
C2985280 BXGD018223 Blood Protein Measurement
C3152182 BXGD018461 Anterior chamber anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C3277117 BXGD018703 Caudal appendage
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3808403 BXGD019546 Large fleshy ears
C3815172 BXGD019672 Interleukin 1 Beta Measurement
C4021789 BXGD020781 Abnormality of the vertebral column
C4021813 BXGD020799 Oral cleft
C4022490 BXGD020906 Prominent coccyx
C4025228 BXGD021599 Partial abdominal muscle agenesis
C4025252 BXGD021607 Abnormal nasal morphology
C4303860 BXGD022569 Craniofacial ulnar renal syndrome
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0003705 Chloride 35.45
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein