Showing entry for Cadherin-related family member 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020185
Protein NameCadherin-related family member 2
Uniport IdQ9BYE9
GeneCDHR2
Gene Id54825
DomainCadherin
Pfam PF00028  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0098609 cell-cell adhesion
Biological Process GO:0044331 cell-cell adhesion mediated by cadherin
Biological Process GO:0030855 epithelial cell differentiation
Biological Process GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Biological Process GO:0090675 intermicrovillar adhesion
Biological Process GO:0060243 negative regulation of cell growth involved in contact inhibition
Biological Process GO:0032532 regulation of microvillus length
molecular function GO:0005509 calcium ion binding
molecular function GO:0050839 cell adhesion molecule binding
cellular component GO:0016324 apical plasma membrane
cellular component GO:0005903 brush border
cellular component GO:0031526 brush border membrane
cellular component GO:0030054 cell junction
cellular component GO:0070062 extracellular exosome
cellular component GO:0031528 microvillus membrane
cellular component GO:0044214 spanning component of plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C1333990 BXGD012670 Hereditary Nonpolyposis Colorectal Cancer Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein