Showing entry for Neurexin-1



                       
General Target Information
BXGT IdBXGT020251
Protein NameNeurexin-1
Uniport IdQ9CS84
GeneNrxn1
Gene Id18189
DomainEGF; Laminin_G_2; Syndecan
Pfam PF00008   PF02210   PF01034  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030534 adult behavior
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0097116 gephyrin clustering involved in postsynaptic density assembly
Biological Process GO:0007612 learning
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly
Biological Process GO:0050885 neuromuscular process controlling balance
Biological Process GO:0031175 neuron projection development
Biological Process GO:0007269 neurotransmitter secretion
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0033138 positive regulation of peptidyl-serine phosphorylation
Biological Process GO:0010739 positive regulation of protein kinase A signaling
Biological Process GO:0051897 positive regulation of protein kinase B signaling
Biological Process GO:1900020 positive regulation of protein kinase C activity
Biological Process GO:0051965 positive regulation of synapse assembly
Biological Process GO:0090129 positive regulation of synapse maturation
Biological Process GO:0051968 positive regulation of synaptic transmission, glutamatergic
Biological Process GO:0097119 postsynaptic density protein 95 clustering
Biological Process GO:0097104 postsynaptic membrane assembly
Biological Process GO:0060134 prepulse inhibition
Biological Process GO:0099054 presynapse assembly
Biological Process GO:2000821 regulation of grooming behavior
Biological Process GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:0099151 regulation of postsynaptic density assembly
Biological Process GO:1905606 regulation of presynapse assembly
Biological Process GO:0007165 signal transduction
Biological Process GO:0035176 social behavior
Biological Process GO:0007416 synapse assembly
Biological Process GO:0099560 synaptic membrane adhesion
Biological Process GO:0006904 vesicle docking involved in exocytosis
Biological Process GO:0071625 vocalization behavior
Biological Process GO:0042297 vocal learning
molecular function GO:0033130 acetylcholine receptor binding
molecular function GO:0005246 calcium channel regulator activity
molecular function GO:0005509 calcium ion binding
molecular function GO:0050839 cell adhesion molecule binding
molecular function GO:0097109 neuroligin family protein binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0004888 transmembrane signaling receptor activity
molecular function GO:0005105 type 1 fibroblast growth factor receptor binding
cellular component GO:0042995 cell projection
cellular component GO:0009986 cell surface
cellular component GO:0030139 endocytic vesicle
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0099059 integral component of presynaptic active zone membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0031965 nuclear membrane
cellular component GO:0005730 nucleolus
cellular component GO:0005886 plasma membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0018397 beta-1,4-mannan 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein