Showing entry for Toll-like receptor 9


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020299
Protein NameToll-like receptor 9
Uniport IdQ9EQU3
GeneTlr9
Gene Id81897
DomainLRR_12; LRR_8; TIR
Pfam PF18837   PF13855   PF01582  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002218 activation of innate immune response
Biological Process GO:1902350 cellular response to chloroquine
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0071248 cellular response to metal ion
Biological Process GO:0001816 cytokine production
Biological Process GO:0050829 defense response to Gram-negative bacterium
Biological Process GO:0051607 defense response to virus
Biological Process GO:0007249 I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0007252 I-kappaB phosphorylation
Biological Process GO:0006955 immune response
Biological Process GO:0045087 innate immune response
Biological Process GO:0030277 maintenance of gastrointestinal epithelium
Biological Process GO:0008584 male gonad development
Biological Process GO:0001774 microglial cell activation
Biological Process GO:0002755 MyD88-dependent toll-like receptor signaling pathway
Biological Process GO:1901895 negative regulation of ATPase-coupled calcium transmembrane transporter activity
Biological Process GO:0032715 negative regulation of interleukin-6 production
Biological Process GO:0032717 negative regulation of interleukin-8 production
Biological Process GO:0032088 negative regulation of NF-kappaB transcription factor activity
Biological Process GO:0034122 negative regulation of toll-like receptor signaling pathway
Biological Process GO:0010508 positive regulation of autophagy
Biological Process GO:0050871 positive regulation of B cell activation
Biological Process GO:0030890 positive regulation of B cell proliferation
Biological Process GO:0032722 positive regulation of chemokine production
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0002639 positive regulation of immunoglobulin production
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0032727 positive regulation of interferon-alpha production
Biological Process GO:0032728 positive regulation of interferon-beta production
Biological Process GO:0032729 positive regulation of interferon-gamma production
Biological Process GO:0032733 positive regulation of interleukin-10 production
Biological Process GO:0032735 positive regulation of interleukin-12 production
Biological Process GO:0032741 positive regulation of interleukin-18 production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0043507 positive regulation of JUN kinase activity
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:1901224 positive regulation of NIK/NF-kappaB signaling
Biological Process GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
Biological Process GO:0034165 positive regulation of toll-like receptor 9 signaling pathway
Biological Process GO:0034123 positive regulation of toll-like receptor signaling pathway
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0032760 positive regulation of tumor necrosis factor production
Biological Process GO:0050864 regulation of B cell activation
Biological Process GO:0045577 regulation of B cell differentiation
Biological Process GO:0050707 regulation of cytokine secretion
Biological Process GO:0002730 regulation of dendritic cell cytokine production
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0001932 regulation of protein phosphorylation
Biological Process GO:0034163 regulation of toll-like receptor 9 signaling pathway
Biological Process GO:0002237 response to molecule of bacterial origin
Biological Process GO:0009615 response to virus
Biological Process GO:0034162 toll-like receptor 9 signaling pathway
Biological Process GO:0002224 toll-like receptor signaling pathway
Biological Process GO:0032640 tumor necrosis factor production
molecular function GO:0005149 interleukin-1 receptor binding
molecular function GO:0038187 pattern recognition receptor activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0035197 siRNA binding
molecular function GO:0004888 transmembrane signaling receptor activity
molecular function GO:0045322 unmethylated CpG binding
cellular component GO:0016324 apical plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0032009 early phagosome
cellular component GO:0036019 endolysosome
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005768 endosome
cellular component GO:0016021 integral component of membrane
cellular component GO:0005764 lysosome
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein