Showing entry for Rap guanine nucleotide exchange factor 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020303
Protein NameRap guanine nucleotide exchange factor 4
Uniport IdQ9EQZ6
GeneRapgef4
Gene Id56508
DomaincNMP_binding; DEP; RasGEF; RasGEF_N
Pfam PF00027   PF00610   PF00617   PF00618  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0017156 calcium-ion regulated exocytosis
Biological Process GO:0019933 cAMP-mediated signaling
Biological Process GO:0030073 insulin secretion
Biological Process GO:0050805 negative regulation of synaptic transmission
Biological Process GO:1904457 positive regulation of neuronal action potential
Biological Process GO:0050714 positive regulation of protein secretion
Biological Process GO:0014911 positive regulation of smooth muscle cell migration
Biological Process GO:0050773 regulation of dendrite development
Biological Process GO:0017157 regulation of exocytosis
Biological Process GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
Biological Process GO:0099175 regulation of postsynapse organization
Biological Process GO:0098693 regulation of synaptic vesicle cycle
Biological Process GO:0007165 signal transduction
Biological Process GO:0007264 small GTPase mediated signal transduction
molecular function GO:0030552 cAMP binding
molecular function GO:0005085 guanyl-nucleotide exchange factor activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0017016 Ras GTPase binding
molecular function GO:0005088 Ras guanyl-nucleotide exchange factor activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005903 brush border
cellular component GO:0005929 cilium
cellular component GO:0044316 cone cell pedicle
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0060076 excitatory synapse
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0030426 growth cone
cellular component GO:0098686 hippocampal mossy fiber to CA3 synapse
cellular component GO:0043025 neuronal cell body
cellular component GO:0001917 photoreceptor inner segment
cellular component GO:0001750 photoreceptor outer segment
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000988 3' 5'-cyclic AMP 329.21
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein