protein

Showing entry for Neuronal acetylcholine receptor subunit beta-2

General Target Information
BXGT Id	BXGT020309
Protein Name	Neuronal acetylcholine receptor subunit beta-2
Uniport Id	Q9ERK7
Gene	Chrnb2
Gene Id	11444
Domain	Neur_chan_LBD; Neur_chan_memb
Pfam	PF02931 PF02932
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0095500	acetylcholine receptor signaling pathway
Biological Process	GO:0001508	action potential
Biological Process	GO:0008306	associative learning
Biological Process	GO:0042113	B cell activation
Biological Process	GO:0035095	behavioral response to nicotine
Biological Process	GO:0006816	calcium ion transport
Biological Process	GO:0021955	central nervous system neuron axonogenesis
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis
Biological Process	GO:0007268	chemical synaptic transmission
Biological Process	GO:0050890	cognition
Biological Process	GO:0001661	conditioned taste aversion
Biological Process	GO:0034220	ion transmembrane transport
Biological Process	GO:0021771	lateral geniculate nucleus development
Biological Process	GO:0007612	learning
Biological Process	GO:0007626	locomotory behavior
Biological Process	GO:0051899	membrane depolarization
Biological Process	GO:0007613	memory
Biological Process	GO:0045759	negative regulation of action potential
Biological Process	GO:0050877	nervous system process
Biological Process	GO:0021631	optic nerve morphogenesis
Biological Process	GO:0030890	positive regulation of B cell proliferation
Biological Process	GO:0033603	positive regulation of dopamine secretion
Biological Process	GO:0032226	positive regulation of synaptic transmission, dopaminergic
Biological Process	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep
Biological Process	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep
Biological Process	GO:0048814	regulation of dendrite morphogenesis
Biological Process	GO:0042053	regulation of dopamine metabolic process
Biological Process	GO:0014059	regulation of dopamine secretion
Biological Process	GO:0042391	regulation of membrane potential
Biological Process	GO:0051963	regulation of synapse assembly
Biological Process	GO:0032225	regulation of synaptic transmission, dopaminergic
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis
Biological Process	GO:1905144	response to acetylcholine
Biological Process	GO:0042220	response to cocaine
Biological Process	GO:0045471	response to ethanol
Biological Process	GO:0001666	response to hypoxia
Biological Process	GO:0035094	response to nicotine
Biological Process	GO:0019233	sensory perception of pain
Biological Process	GO:0007605	sensory perception of sound
Biological Process	GO:0007165	signal transduction
Biological Process	GO:0006939	smooth muscle contraction
Biological Process	GO:0035176	social behavior
Biological Process	GO:0007271	synaptic transmission, cholinergic
Biological Process	GO:0060084	synaptic transmission involved in micturition
Biological Process	GO:0021562	vestibulocochlear nerve development
Biological Process	GO:0008542	visual learning
Biological Process	GO:0007601	visual perception
molecular function	GO:0042166	acetylcholine binding
molecular function	GO:0022848	acetylcholine-gated cation-selective channel activity
molecular function	GO:0015464	acetylcholine receptor activity
molecular function	GO:0008144	drug binding
molecular function	GO:0030594	neurotransmitter receptor activity
molecular function	GO:0044877	protein-containing complex binding
molecular function	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
cellular component	GO:0005892	acetylcholine-gated channel complex
cellular component	GO:0098981	cholinergic synapse
cellular component	GO:0098691	dopaminergic synapse
cellular component	GO:0009897	external side of plasma membrane
cellular component	GO:0005887	integral component of plasma membrane
cellular component	GO:0099060	integral component of postsynaptic specialization membrane
cellular component	GO:0099056	integral component of presynaptic membrane
cellular component	GO:0016020	membrane
cellular component	GO:0043005	neuron projection
cellular component	GO:0005886	plasma membrane
cellular component	GO:0044853	plasma membrane raft
cellular component	GO:0045202	synapse

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000195	O-Methylcorypalline		207.27
BXGC0001451	(S)-Laudanosine		357.44
BXGC0002796	Nicotine		162.23
BXGC0016637	6-Methoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-7-Ol		193.11
BXGC0035349	(+)-Crispine A		233.14
BXGC0040367	7-Methoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-6-Ol		193.11
BXGC0046653	(+/-)Nicotine		162.12
BXGC0049630	6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinoline		191.09

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}