Showing entry for Rho guanine nucleotide exchange factor 7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020315
Protein NameRho guanine nucleotide exchange factor 7
Uniport IdQ9ES28
GeneArhgef7
Gene Id54126
DomainbetaPIX_CC; CH; PH; RhoGEF; RhoGEF67_u1; RhoGEF67_u2; SH3_2
Pfam PF16523   PF00307   PF00169   PF00621   PF07653  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043615 astrocyte cell migration
Biological Process GO:0007030 Golgi organization
Biological Process GO:0002244 hematopoietic progenitor cell differentiation
Biological Process GO:0030032 lamellipodium assembly
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0060124 positive regulation of growth hormone secretion
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0032092 positive regulation of protein binding
Biological Process GO:0098974 postsynaptic actin cytoskeleton organization
Biological Process GO:0099140 presynaptic actin cytoskeleton organization
Biological Process GO:1904424 regulation of GTP binding
Biological Process GO:0007264 small GTPase mediated signal transduction
molecular function GO:0005085 guanyl-nucleotide exchange factor activity
molecular function GO:0019901 protein kinase binding
cellular component GO:0005938 cell cortex
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005925 focal adhesion
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:0030426 growth cone
cellular component GO:0030027 lamellipodium
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0001726 ruffle
cellular component GO:0000322 storage vacuole
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein