protein

Showing entry for Bromodomain-containing protein 4

General Target Information
BXGT Id	BXGT020319
Protein Name	Bromodomain-containing protein 4
Uniport Id	Q9ESU6
Gene	Brd4
Gene Id	57261
Domain	BET; BRD4_CDT; Bromodomain
Pfam	PF17035 PF17105 PF00439
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0007059	chromosome segregation
Biological Process	GO:0044154	histone H3-K14 acetylation
Biological Process	GO:0043983	histone H4-K12 acetylation
Biological Process	GO:0001833	inner cell mass cell proliferation
Biological Process	GO:0043388	positive regulation of DNA binding
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
Biological Process	GO:2001255	positive regulation of histone H3-K36 trimethylation
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process	GO:0045893	positive regulation of transcription, DNA-templated
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
Biological Process	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
Biological Process	GO:0046777	protein autophosphorylation
Biological Process	GO:0006468	protein phosphorylation
Biological Process	GO:0050727	regulation of inflammatory response
Biological Process	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain
Biological Process	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
molecular function	GO:0003682	chromatin binding
molecular function	GO:0003677	DNA binding
molecular function	GO:0034211	GTP-dependent protein kinase activity
molecular function	GO:0070577	lysine-acetylated histone binding
molecular function	GO:0002039	p53 binding
molecular function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity
molecular function	GO:0099122	RNA polymerase II C-terminal domain binding
molecular function	GO:0003712	transcription coregulator activity
cellular component	GO:0000794	condensed nuclear chromosome
cellular component	GO:0008024	cyclin/CDK positive transcription elongation factor complex
cellular component	GO:0000790	nuclear chromatin
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09
BXGC0003705	Chloride		35.45

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}