Showing entry for Cytosolic beta-glucosidase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020447
Protein NameCytosolic beta-glucosidase
Uniport IdQ9H227
GeneGBA3
Gene Id57733
DomainGlyco_hydro_1
Pfam PF00232  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00500 Starch and sucrose metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1901805 beta-glucoside catabolic process
Biological Process GO:0051692 cellular oligosaccharide catabolic process
Biological Process GO:0006683 galactosylceramide catabolic process
Biological Process GO:0006680 glucosylceramide catabolic process
Biological Process GO:0016139 glycoside catabolic process
Biological Process GO:0006687 glycosphingolipid metabolic process
Biological Process GO:0046477 glycosylceramide catabolic process
Biological Process GO:1903017 positive regulation of exo-alpha-sialidase activity
Biological Process GO:0050821 protein stabilization
molecular function GO:0004565 beta-galactosidase activity
molecular function GO:0008422 beta-glucosidase activity
molecular function GO:0004336 galactosylceramidase activity
molecular function GO:0004348 glucosylceramidase activity
molecular function GO:0017042 glycosylceramidase activity
molecular function GO:0102483 scopolin beta-glucosidase activity
cellular component GO:1902494 catalytic complex
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1660662 Glycosphingolipid metabolism
R-HSA-428157 Sphingolipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013170 BXGD000802 Drug habituation Chemically-Induced Disorders; Mental Disorders
C0013222 BXGD000805 Drug Use Disorders Chemically-Induced Disorders; Mental Disorders
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029231 BXGD002125 Organic Mental Disorders, Substance-Induced Chemically-Induced Disorders; Mental Disorders
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038580 BXGD002771 Substance Dependence Chemically-Induced Disorders; Mental Disorders
C0038586 BXGD002772 Substance Use Disorders Chemically-Induced Disorders; Mental Disorders
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0201968 BXGD004061 Cortisol Measurement
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0221406 BXGD004459 Pituitary-dependent Cushing's disease Nervous System Diseases; Endocrine System Diseases
C0236969 BXGD004842 Substance-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0264408 BXGD005387 Childhood asthma Respiratory Tract Diseases; Immune System Diseases
C0271738 BXGD006253 Hypocortisolism secondary to another disorder Endocrine System Diseases
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0740858 BXGD010012 Substance abuse problem Chemically-Induced Disorders; Mental Disorders
C1096184 BXGD011607 West Nile viral infection Infections; Nervous System Diseases
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1608408 BXGD013434 Malignant transformation
C1961835 BXGD016676 Gaucher Disease, Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3495801 BXGD019004 Granulomatosis with polyangiitis Respiratory Tract Diseases; Immune System Diseases; Cardiovascular Diseases
C4050407 BXGD021962 Pauci-immune Glomerulonephritis associated with Granulomatosis with Polyangiitis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4316881 BXGD022709 Prescription Drug Abuse Chemically-Induced Disorders; Mental Disorders
C4727182 BXGD023861 Recurrent Cushing Disease Nervous System Diseases; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0005513 Hexadecanoic acid 256.42
BXGC0005620 beta-D-Glucopyranose 180.16
BXGC0005625 alpha-D-Glucopyranose 180.16
BXGC0015766 Andrographolide 350.21
BXGC0019578 callyspongynic acid 470.28
BXGC0021960 14-Deoxy-15-isopropylidene-11,12-didehydroandrographolide 372.23
BXGC0026906 4-[(E)-2-[(1R,4As,5R,6R,8Ar)-6-Hydroxy-5-(Hydroxymethyl)-5,8A-Dimethyl-2-Methylidene-3,4,4A,6,7,8-Hexahydro-1H-Naphthalen-1-Yl]Ethenyl]-2H-Furan-5-One 332.2
BXGC0030236 Deoxymannojirimycin 163.08
BXGC0032319 L-Ido-1-Deoxynojirimycin 163.08
BXGC0034894 Oleic Acid 282.26
BXGC0041132 Duvoglustat 163.08
BXGC0049562 L-1-Deoxynojirimycin 163.08
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein