Showing entry for S-methylmethionine--homocysteine S-methyltransferase BHMT2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020456
Protein NameS-methylmethionine--homocysteine S-methyltransferase BHMT2
Uniport IdQ9H2M3
GeneBHMT2
Gene Id23743
DomainS-methyl_trans
Pfam PF02574  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00270 Cysteine and methionine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071267 L-methionine salvage
Biological Process GO:0032259 methylation
Biological Process GO:0046500 S-adenosylmethionine metabolic process
Biological Process GO:0033477 S-methylmethionine metabolic process
Biological Process GO:0000096 sulfur amino acid metabolic process
molecular function GO:0061627 S-methylmethionine-homocysteine S-methyltransferase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1614635 Sulfur amino acid metabolism
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0008924 BXGD000574 Cleft upper lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0080178 BXGD003107 Spina Bifida Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0158646 BXGD003897 Cleft palate with cleft lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0373721 BXGD007965 Selenium measurement
C0598608 BXGD009668 Hyperhomocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0810364 BXGD010846 Cleft Lip with or without Cleft Palate
C1837218 BXGD014207 Cleft palate, isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006275 L-Methionine 149.21
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein