Showing entry for Speckle targeted PIP5K1A-regulated poly(A) polymerase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020482
Protein NameSpeckle targeted PIP5K1A-regulated poly(A) polymerase
Uniport IdQ9H6E5
GeneTUT1
Gene Id64852
DomainPAP_assoc; RRM_1; zf-met
Pfam PF03828   PF00076  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006378 mRNA polyadenylation
Biological Process GO:0006397 mRNA processing
Biological Process GO:0098789 pre-mRNA cleavage required for polyadenylation
Biological Process GO:0016180 snRNA processing
Biological Process GO:0034477 U6 snRNA 3'-end processing
molecular function GO:0005524 ATP binding
molecular function GO:0019899 enzyme binding
molecular function GO:0046872 metal ion binding
molecular function GO:0003730 mRNA 3'-UTR binding
molecular function GO:0016779 nucleotidyltransferase activity
molecular function GO:0004652 polynucleotide adenylyltransferase activity
molecular function GO:0003723 RNA binding
molecular function GO:0050265 RNA uridylyltransferase activity
molecular function GO:0017070 U6 snRNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0016607 nuclear speck
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0016529 BXGD001068 Forced expiratory volume function
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0041228 BXGD002900 African Trypanosomiasis Infections
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C4021085 BXGD020544 Abnormality of brain morphology
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein