Showing entry for Solute carrier family 28 member 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020507
Protein NameSolute carrier family 28 member 3
Uniport IdQ9HAS3
GeneSLC28A3
Gene Id64078
DomainGate; Nucleos_tra2_C; Nucleos_tra2_N
Pfam PF07670   PF07662   PF01773  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1901642 nucleoside transmembrane transport
Biological Process GO:1904823 purine nucleobase transmembrane transport
Biological Process GO:0015860 purine nucleoside transmembrane transport
Biological Process GO:0072531 pyrimidine-containing compound transmembrane transport
Biological Process GO:0015864 pyrimidine nucleoside transport
Biological Process GO:0015862 uridine transport
molecular function GO:0005415 nucleoside:sodium symporter activity
molecular function GO:0005337 nucleoside transmembrane transporter activity
molecular function GO:0005345 purine nucleobase transmembrane transporter activity
molecular function GO:0015390 purine-specific nucleoside:sodium symporter activity
molecular function GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity
molecular function GO:0015293 symporter activity
molecular function GO:0015213 uridine transmembrane transporter activity
cellular component GO:0031526 brush border membrane
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023787 BXGD001698 Lipodystrophy Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0027651 BXGD002009 Neoplasms Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0278704 BXGD006567 Malignant Childhood Neoplasm Neoplasms
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0750952 BXGD010263 Biliary Tract Cancer Digestive System Diseases; Neoplasms
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C2363741 BXGD017100 HIV-1 infection
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000480 Phloroacetophenone 168.15
BXGC0002605 Adenosine 267.24
BXGC0003788 Phlororrhizin 436.41
BXGC0008184 Phloretin 274.27
BXGC0014896 1-(2,6-Dihydroxyphenyl)Ethanone 152.05
BXGC0015285 trilobatin 436.14
BXGC0020825 2,4-Dihydroxyacetophenone 152.05
BXGC0044087 Uridine 244.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein