Showing entry for Charged multivesicular body protein 1a


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020543
Protein NameCharged multivesicular body protein 1a
Uniport IdQ9HD42
GeneCHMP1A
Gene Id5119
DomainSnf7
Pfam PF03357  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
4. Cellular Processes 4.2 Cell growth and death hsa04217 Necroptosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0032509 endosome transport via multivesicular body sorting pathway
Biological Process GO:1904903 ESCRT III complex disassembly
Biological Process GO:0016458 gene silencing
Biological Process GO:0045324 late endosome to vacuole transport
Biological Process GO:0061952 midbody abscission
Biological Process GO:0007076 mitotic chromosome condensation
Biological Process GO:0007080 mitotic metaphase plate congression
Biological Process GO:0036258 multivesicular body assembly
Biological Process GO:0045786 negative regulation of cell cycle
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0006997 nucleus organization
Biological Process GO:0015031 protein transport
Biological Process GO:0010824 regulation of centrosome duplication
Biological Process GO:1901673 regulation of mitotic spindle assembly
Biological Process GO:0016192 vesicle-mediated transport
Biological Process GO:0039702 viral budding via host ESCRT complex
molecular function GO:0042802 identical protein binding
molecular function GO:0008237 metallopeptidase activity
molecular function GO:0019904 protein domain specific binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0000794 condensed nuclear chromosome
cellular component GO:0005769 early endosome
cellular component GO:0012505 endomembrane system
cellular component GO:0000815 ESCRT III complex
cellular component GO:0070062 extracellular exosome
cellular component GO:0005815 microtubule organizing center
cellular component GO:0005771 multivesicular body
cellular component GO:0016363 nuclear matrix
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-5663205 Infectious disease
R-HSA-9609646 HCMV Infection
R-HSA-9610379 HCMV Late Events
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0004106 BXGD000254 Astigmatism Eye Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0008489 BXGD000546 Chorea Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0009081 BXGD000581 Congenital clubfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0014877 BXGD000967 Esotropia Eye Diseases; Nervous System Diseases
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0016202 BXGD001050 Flatfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0017654 BXGD001136 Glomerular Filtration Rate
C0020490 BXGD001403 Hyperopia Eye Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0039273 BXGD002806 Talipes cavus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0201976 BXGD004063 Creatinine measurement, serum (procedure)
C0266468 BXGD005677 Congenital pontocerebellar hypoplasia Nervous System Diseases
C0266470 BXGD005678 Cerebellar Hypoplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0406208 BXGD008330 Suntan
C0428883 BXGD008639 Diastolic blood pressure
C0432072 BXGD008718 Dysmorphic features
C0557874 BXGD009444 Global developmental delay
C1261175 BXGD011850 Pontoneocerebellar hypoplasia
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1842688 BXGD014532 Hypoplasia of the brainstem
C1843504 BXGD014589 Pontocerebellar Hypoplasia Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1847514 BXGD014868 Postnatal microcephaly
C1848207 BXGD014916 Poor speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1853743 BXGD015358 Muscular hypotonia of the trunk Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1854882 BXGD015439 Absent speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3554209 BXGD019203 Congenital pontocerebellar hypoplasia type 8 Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4553743 BXGD023548 Spasticity, CTCAE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein