Showing entry for Serine/threonine-protein kinase 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020811
Protein NameSerine/threonine-protein kinase 3
Uniport IdQ9JI10
GeneStk3
Gene Id56274
DomainMst1_SARAH; Pkinase
Pfam PF11629   PF00069  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032147 activation of protein kinase activity
Biological Process GO:0060706 cell differentiation involved in embryonic placenta development
Biological Process GO:0007417 central nervous system development
Biological Process GO:0003157 endocardium development
Biological Process GO:0097284 hepatocyte apoptotic process
Biological Process GO:0035329 hippo signaling
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0046621 negative regulation of organ growth
Biological Process GO:0001841 neural tube formation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
Biological Process GO:0045600 positive regulation of fat cell differentiation
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:0032092 positive regulation of protein binding
Biological Process GO:0051897 positive regulation of protein kinase B signaling
Biological Process GO:0060215 primitive hemopoiesis
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0050821 protein stabilization
Biological Process GO:0060800 regulation of cell differentiation involved in embryonic placenta development
Biological Process GO:0023014 signal transduction by protein phosphorylation
Biological Process GO:0031098 stress-activated protein kinase signaling cascade
molecular function GO:0005524 ATP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein