Showing entry for Serine/threonine-protein kinase WNK1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020816
Protein NameSerine/threonine-protein kinase WNK1
Uniport IdQ9JIH7
GeneWnk1
Gene Id116477
DomainOSR1_C; Pkinase
Pfam PF12202   PF00069  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:1990869 cellular response to chemokine
Biological Process GO:0038116 chemokine (C-C motif) ligand 21 signaling pathway
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0050801 ion homeostasis
Biological Process GO:0006811 ion transport
Biological Process GO:0097022 lymphocyte migration into lymph node
Biological Process GO:0033633 negative regulation of cell-cell adhesion mediated by integrin
Biological Process GO:0034260 negative regulation of GTPase activity
Biological Process GO:0034115 negative regulation of heterotypic cell-cell adhesion
Biological Process GO:0033673 negative regulation of kinase activity
Biological Process GO:1903038 negative regulation of leukocyte cell-cell adhesion
Biological Process GO:0090188 negative regulation of pancreatic juice secretion
Biological Process GO:0010923 negative regulation of phosphatase activity
Biological Process GO:0010766 negative regulation of sodium ion transport
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0090263 positive regulation of canonical Wnt signaling pathway
Biological Process GO:0032414 positive regulation of ion transmembrane transporter activity
Biological Process GO:1903288 positive regulation of potassium ion import across plasma membrane
Biological Process GO:2000651 positive regulation of sodium ion transmembrane transporter activity
Biological Process GO:0003084 positive regulation of systemic arterial blood pressure
Biological Process GO:0010820 positive regulation of T cell chemotaxis
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:1904062 regulation of cation transmembrane transport
Biological Process GO:0050794 regulation of cellular process
Biological Process GO:0002028 regulation of sodium ion transport
Biological Process GO:0023016 signal transduction by trans-phosphorylation
Biological Process GO:0050852 T cell receptor signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0019869 chloride channel inhibitor activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0019902 phosphatase binding
molecular function GO:0019870 potassium channel inhibitor activity
molecular function GO:0030295 protein kinase activator activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0030291 protein serine/threonine kinase inhibitor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein