Showing entry for SH3 and multiple ankyrin repeat domains protein 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020836
Protein NameSH3 and multiple ankyrin repeat domains protein 3
Uniport IdQ9JLU4
GeneShank3
Gene Id59312
DomainAnk_2; PDZ_6; SAM_1; SH3_2
Pfam PF12796   PF17820   PF00536   PF07653  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030534 adult behavior
Biological Process GO:0097113 AMPA glutamate receptor clustering
Biological Process GO:0048854 brain morphogenesis
Biological Process GO:0060997 dendritic spine morphogenesis
Biological Process GO:0001838 embryonic epithelial tube formation
Biological Process GO:0035640 exploration behavior
Biological Process GO:0097117 guanylate kinase-associated protein clustering
Biological Process GO:0007612 learning
Biological Process GO:0007611 learning or memory
Biological Process GO:0040011 locomotion
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0035641 locomotory exploration behavior
Biological Process GO:0060292 long-term synaptic depression
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0099562 maintenance of postsynaptic density structure
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0007613 memory
Biological Process GO:0032232 negative regulation of actin filament bundle assembly
Biological Process GO:0045794 negative regulation of cell volume
Biological Process GO:0050885 neuromuscular process controlling balance
Biological Process GO:0097114 NMDA glutamate receptor clustering
Biological Process GO:2000969 positive regulation of AMPA receptor activity
Biological Process GO:0060999 positive regulation of dendritic spine development
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:1900451 positive regulation of glutamate receptor signaling pathway
Biological Process GO:0048170 positive regulation of long-term neuronal synaptic plasticity
Biological Process GO:1900273 positive regulation of long-term synaptic potentiation
Biological Process GO:0051835 positive regulation of synapse structural plasticity
Biological Process GO:0051968 positive regulation of synaptic transmission, glutamatergic
Biological Process GO:0097107 postsynaptic density assembly
Biological Process GO:1904717 regulation of AMPA glutamate receptor clustering
Biological Process GO:2000311 regulation of AMPA receptor activity
Biological Process GO:2000822 regulation of behavioral fear response
Biological Process GO:0061001 regulation of dendritic spine morphogenesis
Biological Process GO:2000821 regulation of grooming behavior
Biological Process GO:1900452 regulation of long-term synaptic depression
Biological Process GO:1900271 regulation of long-term synaptic potentiation
Biological Process GO:0050807 regulation of synapse organization
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0035176 social behavior
Biological Process GO:0021773 striatal medium spiny neuron differentiation
Biological Process GO:0007416 synapse assembly
Biological Process GO:0051124 synaptic growth at neuromuscular junction
Biological Process GO:0071625 vocalization behavior
Biological Process GO:0042297 vocal learning
molecular function GO:0003779 actin binding
molecular function GO:0042802 identical protein binding
molecular function GO:0035255 ionotropic glutamate receptor binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0043621 protein self-association
molecular function GO:0097110 scaffold protein binding
molecular function GO:0017124 SH3 domain binding
molecular function GO:0030159 signaling receptor complex adaptor activity
molecular function GO:0098919 structural constituent of postsynaptic density
molecular function GO:0030160 synaptic receptor adaptor activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0060170 ciliary membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0043005 neuron projection
cellular component GO:0044309 neuron spine
cellular component GO:0014069 postsynaptic density
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein