Showing entry for Bifunctional polynucleotide phosphatase/kinase



                       
General Target Information
BXGT IdBXGT020837
Protein NameBifunctional polynucleotide phosphatase/kinase
Uniport IdQ9JLV6
GenePnkp
Gene Id
DomainA_33; FHA_2; PNK3P
Pfam PF17913   PF08645  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016311 dephosphorylation
Biological Process GO:0042769 DNA damage response, detection of DNA damage
Biological Process GO:0006281 DNA repair
Biological Process GO:0010836 negative regulation of protein ADP-ribosylation
Biological Process GO:0046939 nucleotide phosphorylation
Biological Process GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining
Biological Process GO:0051973 positive regulation of telomerase activity
Biological Process GO:1904355 positive regulation of telomere capping
Biological Process GO:0032212 positive regulation of telomere maintenance via telomerase
Biological Process GO:0006979 response to oxidative stress
molecular function GO:0005524 ATP binding
molecular function GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0050145 nucleoside monophosphate kinase activity
molecular function GO:0046403 polynucleotide 3'-phosphatase activity
cellular component GO:0005739 mitochondrion
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein