Showing entry for cAMP-specific 3',5'-cyclic phosphodiesterase 7B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021142
Protein NamecAMP-specific 3',5'-cyclic phosphodiesterase 7B
Uniport IdQ9NP56
GenePDE7B
Gene Id27115
DomainPDEase_I
Pfam PF00233  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
6. Human Diseases 6.5 Substance dependence hsa05032 Morphine addiction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006198 cAMP catabolic process
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007165 signal transduction
molecular function GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005829 cytosol
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418555 G alpha (s) signalling events
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0012813 BXGD000791 Diverticulitis Digestive System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017612 BXGD001129 Glaucoma, Open-Angle Eye Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0027651 BXGD002009 Neoplasms Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0040420 BXGD002861 Tonometry
C0201899 BXGD004056 Aspartate aminotransferase measurement
C0201968 BXGD004061 Cortisol Measurement
C0264408 BXGD005387 Childhood asthma Respiratory Tract Diseases; Immune System Diseases
C0280141 BXGD006716 Acute Undifferentiated Leukemia
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0427460 BXGD008616 Red cell distribution width determination
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0751778 BXGD010587 Myoclonic Epilepsies, Progressive Nervous System Diseases
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1378511 BXGD012932 Undifferentiated leukemia
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3839868 BXGD019788 Cytogenetically normal acute myeloid leukemia Neoplasms
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001502 Caffeine 194.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein