Showing entry for Ras-related GTP-binding protein D


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021165
Protein NameRas-related GTP-binding protein D
Uniport IdQ9NQL2
GeneRRAGD
Gene Id58528
DomainGtr1_RagA
Pfam PF04670  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04140 Autophagy - animal
3. Environmental Information Processing 3.2 Signal transduction hsa04150 mTOR signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007050 cell cycle arrest
Biological Process GO:0034613 cellular protein localization
Biological Process GO:0071230 cellular response to amino acid stimulus
Biological Process GO:0071233 cellular response to leucine
Biological Process GO:1990253 cellular response to leucine starvation
Biological Process GO:0009267 cellular response to starvation
Biological Process GO:1904263 positive regulation of TORC1 signaling
Biological Process GO:0032008 positive regulation of TOR signaling
Biological Process GO:0010506 regulation of autophagy
Biological Process GO:0016241 regulation of macroautophagy
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0051020 GTPase binding
molecular function GO:0005525 GTP binding
molecular function GO:0046982 protein heterodimerization activity
cellular component GO:0005813 centrosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0034448 EGO complex
cellular component GO:1990131 Gtr1-Gtr2 GTPase complex
cellular component GO:0005764 lysosome
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-162582 Signal Transduction
R-HSA-1632852 Macroautophagy
R-HSA-165159 MTOR signalling
R-HSA-166208 mTORC1-mediated signalling
R-HSA-212436 Generic Transcription Pathway
R-HSA-2262752 Cellular responses to stress
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK
R-HSA-5628897 TP53 Regulates Metabolic Genes
R-HSA-6807070 PTEN Regulation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8943724 Regulation of PTEN gene transcription
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9612973 Autophagy
R-HSA-9639288 Amino acids regulate mTORC1
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0017654 BXGD001136 Glomerular Filtration Rate
C0201976 BXGD004063 Creatinine measurement, serum (procedure)
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein