Showing entry for Glutaredoxin-2, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021200
Protein NameGlutaredoxin-2, mitochondrial
Uniport IdQ9NS18
GeneGLRX2
Gene Id51022
DomainGlutaredoxin
Pfam PF00462  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0006915 apoptotic process
Biological Process GO:0030154 cell differentiation
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0071451 cellular response to superoxide
Biological Process GO:0042262 DNA protection
Biological Process GO:0006749 glutathione metabolic process
Biological Process GO:0009966 regulation of signal transduction
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0010033 response to organic substance
Biological Process GO:0051775 response to redox state
Biological Process GO:0009266 response to temperature stimulus
molecular function GO:0051537 2 iron, 2 sulfur cluster binding
molecular function GO:0008794 arsenate reductase (glutaredoxin) activity
molecular function GO:0009055 electron transfer activity
molecular function GO:0015038 glutathione disulfide oxidoreductase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0003756 protein disulfide isomerase activity
molecular function GO:0015035 protein disulfide oxidoreductase activity
cellular component GO:0030425 dendrite
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0043025 neuronal cell body
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C2985280 BXGD018223 Blood Protein Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000989 Glutathione 307.32
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein