Showing entry for Serine palmitoyltransferase 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021217
Protein NameSerine palmitoyltransferase 3
Uniport IdQ9NUV7
GeneSPTLC3
Gene Id55304
DomainAminotran_1_2
Pfam PF00155  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00600 Sphingolipid metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
3. Environmental Information Processing 3.2 Signal transduction hsa04071 Sphingolipid signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046513 ceramide biosynthetic process
Biological Process GO:0046520 sphingoid biosynthetic process
Biological Process GO:0030148 sphingolipid biosynthetic process
Biological Process GO:0046512 sphingosine biosynthetic process
molecular function GO:0030170 pyridoxal phosphate binding
molecular function GO:0004758 serine C-palmitoyltransferase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0017059 serine C-palmitoyltransferase complex
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1660661 Sphingolipid de novo biosynthesis
R-HSA-428157 Sphingolipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0151313 BXGD003413 Sensory neuropathy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0233849 BXGD004621 Personality Traits Behavior and Behavior Mechanisms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0476227 BXGD008981 pricking of skin
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0752125 BXGD010673 Spinocerebellar Ataxia Type 7 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1266086 BXGD011952 Polymorphous low grade adenocarcinoma
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0043088 Pyridoxal Phosphate 247.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein