Showing entry for ATP-dependent RNA helicase DDX18


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021226
Protein NameATP-dependent RNA helicase DDX18
Uniport IdQ9NVP1
GeneDDX18
Gene Id8886
DomainDEAD; DUF4217; Helicase_C
Pfam PF00270   PF13959   PF00271  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
molecular function GO:0005524 ATP binding
molecular function GO:0003723 RNA binding
molecular function GO:0003724 RNA helicase activity
cellular component GO:0005694 chromosome
cellular component GO:0016020 membrane
cellular component GO:0005730 nucleolus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0243050 BXGD005212 Cardiovascular Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0815107 BXGD010861 psychological distress
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein