Showing entry for tRNA-dihydrouridine(20) synthase [NAD(P)+]-like


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021244
Protein NametRNA-dihydrouridine(20) synthase [NAD(P)+]-like
Uniport IdQ9NX74
GeneDUS2
Gene Id54920
Domaindsrm; Dus
Pfam PF00035   PF01207  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:0002943 tRNA dihydrouridine synthesis
molecular function GO:0003725 double-stranded RNA binding
molecular function GO:0050660 flavin adenine dinucleotide binding
molecular function GO:0010181 FMN binding
molecular function GO:0070402 NADPH binding
molecular function GO:0004860 protein kinase inhibitor activity
molecular function GO:0102264 tRNA-dihydrouridine20 synthase activity
molecular function GO:0017150 tRNA dihydrouridine synthase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
Reactome
Pathway Id Pathway Name
R-HSA-6782315 tRNA modification in the nucleus and cytosol
R-HSA-72306 tRNA processing
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein