Showing entry for Voltage-dependent T-type calcium channel subunit alpha-1I


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021293
Protein NameVoltage-dependent T-type calcium channel subunit alpha-1I
Uniport IdQ9P0X4
GeneCACNA1I
Gene Id8911
DomainIon_trans
Pfam PF00520  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
5. Organismal Systems 5.10 Environmental adaptation hsa04713 Circadian entrainment
5. Organismal Systems 5.2 Endocrine system hsa04925 Aldosterone synthesis and secretion
5. Organismal Systems 5.2 Endocrine system hsa04927 Cortisol synthesis and secretion
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04934 Cushing syndrome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070509 calcium ion import
Biological Process GO:0030317 flagellated sperm motility
Biological Process GO:0086010 membrane depolarization during action potential
Biological Process GO:0019228 neuronal action potential
Biological Process GO:0045956 positive regulation of calcium ion-dependent exocytosis
Biological Process GO:0034765 regulation of ion transmembrane transport
Biological Process GO:0007165 signal transduction
Biological Process GO:0030431 sleep
molecular function GO:0005261 cation channel activity
molecular function GO:0008332 low voltage-gated calcium channel activity
molecular function GO:0005245 voltage-gated calcium channel activity
molecular function GO:0005248 voltage-gated sodium channel activity
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0005891 voltage-gated calcium channel complex
cellular component GO:0001518 voltage-gated sodium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-375165 NCAM signaling for neurite out-growth
R-HSA-419037 NCAM1 interactions
R-HSA-422475 Axon guidance
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008074 BXGD000519 Child Development Disorders, Pervasive Mental Disorders
C0014548 BXGD000928 Epilepsy, Generalized Nervous System Diseases
C0014553 BXGD000931 Absence Epilepsy Nervous System Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0035227 BXGD002514 Respiratory Function Tests
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0596887 BXGD009648 mathematical ability
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4281785 BXGD022415 Childhood Absence Epilepsy Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003611 Latex 416.57
BXGC0006372 Ergocalciferol 396.65
BXGC0024988 Nifedipine 346.12
BXGC0027854 Ethosuximide 141.08
BXGC0040150 Cannabidiol 314.22
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein