protein

Showing entry for Bile salt export pump

General Target Information
BXGT Id	BXGT021389
Protein Name	Bile salt export pump
Uniport Id	Q9QY30
Gene	Abcb11
Gene Id	27413
Domain	ABC_membrane; ABC_tran
Pfam	PF00664 PF00005
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0015721	bile acid and bile salt transport
Biological Process	GO:0008206	bile acid metabolic process
Biological Process	GO:0015722	canalicular bile acid transport
Biological Process	GO:0042632	cholesterol homeostasis
Biological Process	GO:0046618	drug export
Biological Process	GO:0017144	drug metabolic process
Biological Process	GO:0006855	drug transmembrane transport
Biological Process	GO:0006631	fatty acid metabolic process
Biological Process	GO:0055088	lipid homeostasis
Biological Process	GO:0055091	phospholipid homeostasis
Biological Process	GO:0120189	positive regulation of bile acid secretion
Biological Process	GO:0016567	protein ubiquitination
Biological Process	GO:1904251	regulation of bile acid metabolic process
Biological Process	GO:0031998	regulation of fatty acid beta-oxidation
Biological Process	GO:0042493	response to drug
Biological Process	GO:0055085	transmembrane transport
molecular function	GO:0016887	ATPase activity
molecular function	GO:0015432	ATPase-coupled bile acid transmembrane transporter activity
molecular function	GO:0042626	ATPase-coupled transmembrane transporter activity
molecular function	GO:0008559	ATPase-coupled xenobiotic transmembrane transporter activity
molecular function	GO:0005524	ATP binding
molecular function	GO:0015125	bile acid transmembrane transporter activity
molecular function	GO:0015126	canalicular bile acid transmembrane transporter activity
molecular function	GO:0015144	carbohydrate transmembrane transporter activity
cellular component	GO:0045177	apical part of cell
cellular component	GO:0016324	apical plasma membrane
cellular component	GO:0009986	cell surface
cellular component	GO:0005768	endosome
cellular component	GO:0005794	Golgi apparatus
cellular component	GO:0000139	Golgi membrane
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0046581	intercellular canaliculus
cellular component	GO:0046691	intracellular canaliculus
cellular component	GO:0016020	membrane
cellular component	GO:0005886	plasma membrane
cellular component	GO:0055037	recycling endosome
cellular component	GO:0055038	recycling endosome membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0022231	Ursodiol		392.29
BXGC0022544	Digoxin		780.43
BXGC0025658	Vinblastine		810.42
BXGC0027374	Glyburide		493.14
BXGC0027421	Paclitaxel		853.33
BXGC0034768	Vincristine		824.4
BXGC0052374	Reserpine		608.27

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}