protein

Showing entry for cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT021391
Protein Name	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Uniport Id	Q9QYJ6
Gene	Pde10a
Gene Id	63885
Domain	GAF; PDEase_I
Pfam	PF01590 PF00233
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006198	cAMP catabolic process
Biological Process	GO:0046069	cGMP catabolic process
Biological Process	GO:0043951	negative regulation of cAMP-mediated signaling
Biological Process	GO:0010754	negative regulation of cGMP-mediated signaling
Biological Process	GO:0043949	regulation of cAMP-mediated signaling
Biological Process	GO:0010738	regulation of protein kinase A signaling
Biological Process	GO:0007165	signal transduction
molecular function	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity
molecular function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
molecular function	GO:0030552	cAMP binding
molecular function	GO:0030553	cGMP binding
molecular function	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
molecular function	GO:0004112	cyclic-nucleotide phosphodiesterase activity
molecular function	GO:0046872	metal ion binding
cellular component	GO:0005737	cytoplasm
cellular component	GO:0016020	membrane
cellular component	GO:0043025	neuronal cell body
cellular component	GO:0043204	perikaryon

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000202	Papaverine		339.39
BXGC0000441	Dimethyl sulfoxide		78.13
BXGC0002588	Magnesium		24.31

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}