Showing entry for Receptor-interacting serine/threonine-protein kinase 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021397
Protein NameReceptor-interacting serine/threonine-protein kinase 3
Uniport IdQ9QZL0
GeneRipk3
Gene Id56532
DomainPkinase; RHIM
Pfam PF00069   PF12721  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032147 activation of protein kinase activity
Biological Process GO:1990000 amyloid fibril formation
Biological Process GO:0006915 apoptotic process
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:0051607 defense response to virus
Biological Process GO:0097528 execution phase of necroptosis
Biological Process GO:0007249 I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0048535 lymph node development
Biological Process GO:0070266 necroptotic process
Biological Process GO:0097527 necroptotic signaling pathway
Biological Process GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Biological Process GO:0051351 positive regulation of ligase activity
Biological Process GO:0060545 positive regulation of necroptotic process
Biological Process GO:0010940 positive regulation of necrotic cell death
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0051353 positive regulation of oxidoreductase activity
Biological Process GO:0010922 positive regulation of phosphatase activity
Biological Process GO:2000379 positive regulation of reactive oxygen species metabolic process
Biological Process GO:0097300 programmed necrotic cell death
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0046006 regulation of activated T cell proliferation
Biological Process GO:0070235 regulation of activation-induced cell death of T cells
Biological Process GO:0002819 regulation of adaptive immune response
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:2000452 regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
Biological Process GO:0032649 regulation of interferon-gamma production
Biological Process GO:2000377 regulation of reactive oxygen species metabolic process
Biological Process GO:0001914 regulation of T cell mediated cytotoxicity
Biological Process GO:0007165 signal transduction
Biological Process GO:0048536 spleen development
Biological Process GO:0033077 T cell differentiation in thymus
Biological Process GO:0043029 T cell homeostasis
Biological Process GO:0048538 thymus development
Biological Process GO:0016032 viral process
molecular function GO:0005524 ATP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004704 NF-kappaB-inducing kinase activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein