Showing entry for tRNA (guanine-N(7)-)-methyltransferase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021659
Protein NametRNA (guanine-N(7)-)-methyltransferase
Uniport IdQ9UBP6
GeneMETTL1
Gene Id4234
DomainMethyltransf_4
Pfam PF02390  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0036265 RNA (guanine-N7)-methylation
Biological Process GO:0030488 tRNA methylation
Biological Process GO:0006400 tRNA modification
molecular function GO:0008176 tRNA (guanine-N7-)-methyltransferase activity
molecular function GO:0000049 tRNA binding
cellular component GO:0005829 cytosol
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0043527 tRNA methyltransferase complex
Reactome
Pathway Id Pathway Name
R-HSA-6782315 tRNA modification in the nucleus and cytosol
R-HSA-72306 tRNA processing
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein