protein

Showing entry for Bromodomain adjacent to zinc finger domain protein 2A

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT021719
Protein Name	Bromodomain adjacent to zinc finger domain protein 2A
Uniport Id	Q9UIF9
Gene	BAZ2A
Gene Id	11176
Domain	Bromodomain; DDT; MBD; PHD; WHIM1; WSD
Pfam	PF00439 PF02791 PF01429 PF00628 PF15612 PF15613
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006338	chromatin remodeling
Biological Process	GO:0006306	DNA methylation
Biological Process	GO:0016575	histone deacetylation
Biological Process	GO:0000183	rDNA heterochromatin assembly
Biological Process	GO:0006355	regulation of transcription, DNA-templated
Biological Process	GO:0006351	transcription, DNA-templated
molecular function	GO:0042393	histone binding
molecular function	GO:0070577	lysine-acetylated histone binding
molecular function	GO:0046872	metal ion binding
molecular function	GO:0016922	nuclear receptor binding
molecular function	GO:0003723	RNA binding
molecular function	GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding
cellular component	GO:0005677	chromatin silencing complex
cellular component	GO:0005829	cytosol
cellular component	GO:0042025	host cell nucleus
cellular component	GO:0016607	nuclear speck
cellular component	GO:0005730	nucleolus
cellular component	GO:0033553	rDNA heterochromatin

Reactome

Pathway Id	Pathway Name
R-HSA-212165	Epigenetic regulation of gene expression
R-HSA-427413	NoRC negatively regulates rRNA expression
R-HSA-5250941	Negative epigenetic regulation of rRNA expression
R-HSA-74160	Gene expression (Transcription)

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027819	BXGD002043	Neuroblastoma	Neoplasms
C0032181	BXGD002332	Platelet Count measurement
C0033578	BXGD002408	Prostatic Neoplasms	Neoplasms; Male Urogenital Diseases
C0200665	BXGD004045	Platelet mean volume determination (procedure)
C0376358	BXGD007992	Malignant neoplasm of prostate	Neoplasms; Male Urogenital Diseases
C0600139	BXGD009695	Prostate carcinoma	Neoplasms; Male Urogenital Diseases
C0700095	BXGD009875	Central neuroblastoma	Neoplasms; Nervous System Diseases
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C4086165	BXGD022126	Childhood Neuroblastoma	Neoplasms

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09
BXGC0002588	Magnesium		24.31
BXGC0002591	Potassium		39.1

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}