Showing entry for C-type lectin domain family 4 member E


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021770
Protein NameC-type lectin domain family 4 member E
Uniport IdQ9ULY5
GeneCLEC4E
Gene Id26253
DomainLectin_C
Pfam PF00059  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04625 C-type lectin receptor signaling pathway
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05152 Tuberculosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042742 defense response to bacterium
Biological Process GO:0038094 Fc-gamma receptor signaling pathway
Biological Process GO:0045087 innate immune response
Biological Process GO:0002221 pattern recognition receptor signaling pathway
Biological Process GO:0050715 positive regulation of cytokine secretion
Biological Process GO:0002223 stimulatory C-type lectin receptor signaling pathway
Biological Process GO:0002292 T cell differentiation involved in immune response
molecular function GO:0005509 calcium ion binding
molecular function GO:0030246 carbohydrate binding
molecular function GO:0038187 pattern recognition receptor activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-5621480 Dectin-2 family
R-HSA-5621480 Dectin-2 family
R-HSA-5621481 C-type lectin receptors (CLRs)
R-HSA-5621481 C-type lectin receptors (CLRs)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0008149 BXGD000520 Chlamydia Infections Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0022568 BXGD001552 Keratitis Eye Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023896 BXGD001718 Alcoholic Liver Diseases Digestive System Diseases; Chemically-Induced Disorders
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041327 BXGD002916 Tuberculosis, Pulmonary Infections; Respiratory Tract Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0150055 BXGD003401 Chronic pain Pathological Conditions, Signs and Symptoms
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0276655 BXGD006439 Infection by Aspergillus fumigatus Infections
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0585186 BXGD009585 Cutaneous hypersensitivity Skin and Connective Tissue Diseases; Immune System Diseases
C0849640 BXGD010889 skin damage
C0856742 BXGD011111 Post MI Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1262117 BXGD011871 Fungal keratitis Pathological Conditions, Signs and Symptoms; Infections; Eye Diseases
C1535939 BXGD013323 Pneumocystis jiroveci pneumonia Infections; Respiratory Tract Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0038316 Cholesterol 386.35
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein