Showing entry for Protein kinase C and casein kinase substrate in neurons protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021786
Protein NameProtein kinase C and casein kinase substrate in neurons protein 2
Uniport IdQ9UNF0
GenePACSIN2
Gene Id11252
DomainFCH; SH3_1
Pfam PF00611   PF00018  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0070836 caveola assembly
Biological Process GO:0072584 caveolin-mediated endocytosis
Biological Process GO:0048858 cell projection morphogenesis
Biological Process GO:0007010 cytoskeleton organization
Biological Process GO:0061024 membrane organization
Biological Process GO:0045806 negative regulation of endocytosis
Biological Process GO:0097320 plasma membrane tubulation
Biological Process GO:0036010 protein localization to endosome
Biological Process GO:0030100 regulation of endocytosis
molecular function GO:0045296 cadherin binding
molecular function GO:0008092 cytoskeletal protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:0070300 phosphatidic acid binding
molecular function GO:0005543 phospholipid binding
molecular function GO:0005215 transporter activity
cellular component GO:0005901 caveola
cellular component GO:0005911 cell-cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0019898 extrinsic component of membrane
cellular component GO:0005925 focal adhesion
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016607 nuclear speck
cellular component GO:0005886 plasma membrane
cellular component GO:0055038 recycling endosome membrane
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-5653656 Vesicle-mediated transport
R-HSA-8856828 Clathrin-mediated endocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0032181 BXGD002332 Platelet Count measurement
C0087031 BXGD003319 Juvenile-Onset Still Disease Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0200635 BXGD004041 Lymphocyte Count measurement
C0200665 BXGD004045 Platelet mean volume determination (procedure)
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3714758 BXGD019431 Juvenile psoriatic arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3828530 BXGD019744 Platelet Component Distribution Width Measurement
C4552091 BXGD023485 Polyarthritis, Juvenile, Rheumatoid Factor Negative Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4704862 BXGD023681 Polyarthritis, Juvenile, Rheumatoid Factor Positive Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein