Showing entry for ATP-sensitive inward rectifier potassium channel 14



                       
General Target Information
BXGT IdBXGT021794
Protein NameATP-sensitive inward rectifier potassium channel 14
Uniport IdQ9UNX9
GeneKCNJ14
Gene Id3770
DomainIRK; IRK_C
Pfam PF01007   PF17655  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.6 Nervous system hsa04725 Cholinergic synapse
5. Organismal Systems 5.2 Endocrine system hsa04921 Oxytocin signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0061337 cardiac conduction
Biological Process GO:1990573 potassium ion import across plasma membrane
Biological Process GO:0034765 regulation of ion transmembrane transport
molecular function GO:0005242 inward rectifier potassium channel activity
cellular component GO:0030425 dendrite
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0008076 voltage-gated potassium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296053 Classical Kir channels
R-HSA-1296065 Inwardly rectifying K+ channels
R-HSA-1296071 Potassium Channels
R-HSA-397014 Muscle contraction
R-HSA-5576886 Phase 4 - resting membrane potential
R-HSA-5576891 Cardiac conduction
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0046755 Yohimbine 354.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein