Showing entry for Brain-specific angiogenesis inhibitor 1-associated protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021809
Protein NameBrain-specific angiogenesis inhibitor 1-associated protein 2
Uniport IdQ9UQB8
GeneBAIAP2
Gene Id10458
DomainIMD; SH3_9
Pfam PF08397   PF14604  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04520 Adherens junction
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051764 actin crosslink formation
Biological Process GO:0051017 actin filament bundle assembly
Biological Process GO:0007409 axonogenesis
Biological Process GO:0007420 brain development
Biological Process GO:0071364 cellular response to epidermal growth factor stimulus
Biological Process GO:1905232 cellular response to L-glutamate
Biological Process GO:0016358 dendrite development
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0008286 insulin receptor signaling pathway
Biological Process GO:0007009 plasma membrane organization
Biological Process GO:2000251 positive regulation of actin cytoskeleton reorganization
Biological Process GO:0030838 positive regulation of actin filament polymerization
Biological Process GO:0061003 positive regulation of dendritic spine morphogenesis
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:0035418 protein localization to synapse
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0009617 response to bacterium
Biological Process GO:0048010 vascular endothelial growth factor receptor signaling pathway
molecular function GO:0098641 cadherin binding involved in cell-cell adhesion
molecular function GO:0008093 cytoskeletal anchor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0070064 proline-rich region binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0001221 transcription cofactor binding
cellular component GO:0005912 adherens junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043198 dendritic shaft
cellular component GO:0061846 dendritic spine cytoplasm
cellular component GO:0060076 excitatory synapse
cellular component GO:0070062 extracellular exosome
cellular component GO:0030175 filopodium
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005874 microtubule
cellular component GO:0043025 neuronal cell body
cellular component GO:0061845 neuron projection branch point
cellular component GO:0044306 neuron projection terminus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0099524 postsynaptic cytosol
cellular component GO:0014069 postsynaptic density
cellular component GO:0099523 presynaptic cytosol
cellular component GO:0005791 rough endoplasmic reticulum
cellular component GO:0001726 ruffle
cellular component GO:0098685 Schaffer collateral - CA1 synapse
cellular component GO:0030141 secretory granule
cellular component GO:0097060 synaptic membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-194138 Signaling by VEGF
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-195258 RHO GTPase Effectors
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs
R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9658195 Leishmania infection
R-HSA-9658195 Leishmania infection
R-HSA-9664407 Parasite infection
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003868 BXGD000233 Arthritis, Gouty Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0004936 BXGD000295 Mental disorders Mental Disorders
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0018099 BXGD001172 Gout Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0202239 BXGD004087 Uric acid measurement (procedure)
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0334054 BXGD006984 cystic disease
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0424101 BXGD008519 Inattention
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0424678 BXGD008537 Lean body mass
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0557874 BXGD009444 Global developmental delay
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0596887 BXGD009648 mathematical ability
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1285654 BXGD012172 Memory performance
C1305855 BXGD012348 Body mass index
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0004266 2-Propanol 60.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein