protein

Showing entry for NADPH oxidase 1

General Target Information
BXGT Id	BXGT021945
Protein Name	NADPH oxidase 1
Uniport Id	Q9WV87
Gene	Nox1
Gene Id	114243
Domain	FAD_binding_8; Ferric_reduct; NAD_binding_6
Pfam	PF08022 PF01794 PF08030
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0001525	angiogenesis
Biological Process	GO:0016477	cell migration
Biological Process	GO:0071455	cellular response to hyperoxia
Biological Process	GO:1990451	cellular stress response to acidic pH
Biological Process	GO:0006952	defense response
Biological Process	GO:0030198	extracellular matrix organization
Biological Process	GO:0042743	hydrogen peroxide metabolic process
Biological Process	GO:0051454	intracellular pH elevation
Biological Process	GO:0055114	oxidation-reduction process
Biological Process	GO:0072592	oxygen metabolic process
Biological Process	GO:0008284	positive regulation of cell population proliferation
Biological Process	GO:0045726	positive regulation of integrin biosynthetic process
Biological Process	GO:0046330	positive regulation of JNK cascade
Biological Process	GO:0043410	positive regulation of MAPK cascade
Biological Process	GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production
Biological Process	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
Biological Process	GO:0000302	response to reactive oxygen species
Biological Process	GO:0007165	signal transduction
Biological Process	GO:0042554	superoxide anion generation
molecular function	GO:0046872	metal ion binding
molecular function	GO:0016174	NAD(P)H oxidase (H(2)O(2)-forming activity
molecular function	GO:0048365	Rac GTPase binding
molecular function	GO:0016175	superoxide-generating NADPH oxidase activity
cellular component	GO:0030054	cell junction
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005769	early endosome
cellular component	GO:0005768	endosome
cellular component	GO:0071438	invadopodium membrane
cellular component	GO:0043020	NADPH oxidase complex
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0001742	Eupafolin		316.26

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}