Showing entry for Estrogen receptor beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022188
Protein NameEstrogen receptor beta
Uniport IdQ9XSB5
GeneESR2
Gene Id281146
DomainERbeta_N; Hormone_recep; zf-C4
Pfam PF12497   PF00104   PF00105  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0030520 intracellular estrogen receptor signaling pathway
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
molecular function GO:0019899 enzyme binding
molecular function GO:0030284 estrogen receptor activity
molecular function GO:0034056 estrogen response element binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0070491 repressing transcription factor binding
molecular function GO:0005496 steroid binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005739 mitochondrion
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0003707 Estrogen 268.36
BXGC0006362 Estrone 270.37
BXGC0033999 Zuclomiphene 405.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein