Showing entry for GDP-fucose protein O-fucosyltransferase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022232
Protein NameGDP-fucose protein O-fucosyltransferase 2
Uniport IdQ9Y2G5
GenePOFUT2
Gene Id23275
DomainO-FucT
Pfam PF10250  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00514 Other types of O-glycan biosynthesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006004 fucose metabolic process
Biological Process GO:0001707 mesoderm formation
Biological Process GO:1903334 positive regulation of protein folding
Biological Process GO:0036066 protein O-linked fucosylation
Biological Process GO:0010717 regulation of epithelial to mesenchymal transition
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0051046 regulation of secretion
molecular function GO:0046922 peptide-O-fucosyltransferase activity
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005794 Golgi apparatus
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-5173105 O-linked glycosylation
R-HSA-5173214 O-glycosylation of TSR domain-containing proteins
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0024530 BXGD001783 Malaria Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0265259 BXGD005487 Popliteal pterygium syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Musculoskeletal Diseases; Male Urogenital Diseases; Stomatognathic Diseases
C0282577 BXGD006816 Congenital Disorders of Glycosylation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0796012 BXGD010777 Krause-Kivlin syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1456687 BXGD013122 Polio and Post-Polio Syndrome Infections
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0012750 Guanosine Diphosphate Fucose 589.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein