Showing entry for Microtubule-associated serine/threonine-protein kinase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022234
Protein NameMicrotubule-associated serine/threonine-protein kinase 1
Uniport IdQ9Y2H9
GeneMAST1
Gene Id22983
DomainDUF1908; PDZ_6; Pkinase
Pfam PF08926   PF17820   PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007420 brain development
Biological Process GO:0007010 cytoskeleton organization
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0006468 protein phosphorylation
molecular function GO:0005524 ATP binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0008017 microtubule binding
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0030425 dendrite
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0014772 BXGD000948 Red Blood Cell Count measurement
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026351 BXGD001900 Moderate intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0027651 BXGD002009 Neoplasms Neoplasms
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0200637 BXGD004042 Monocyte count procedure
C0206161 BXGD004167 Reticulocyte count (procedure)
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0231686 BXGD004508 Gait, Unsteady Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266470 BXGD005678 Cerebellar Hypoplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0346153 BXGD007781 Breast Cancer, Familial Neoplasms; Skin and Connective Tissue Diseases
C0424503 BXGD008532 Dysmorphic facies
C0427460 BXGD008616 Red cell distribution width determination
C0432072 BXGD008718 Dysmorphic features
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0557874 BXGD009444 Global developmental delay
C0596887 BXGD009648 mathematical ability
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0750880 BXGD010239 Monocyte count result
C0856975 BXGD011127 Autistic behavior Behavior and Behavior Mechanisms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1335177 BXGD012771 Ovarian Serous Adenocarcinoma Neoplasms
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1842688 BXGD014532 Hypoplasia of the brainstem
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2720434 BXGD017532 Macroencephaly
C3278923 BXGD018748 Dilated ventricles (finding)
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
C4748927 BXGD024039 MEGA-CORPUS-CALLOSUM SYNDROME WITH CEREBELLAR HYPOPLASIA AND CORTICAL MALFORMATIONS
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein