Showing entry for Netrin-G1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022236
Protein NameNetrin-G1
Uniport IdQ9Y2I2
GeneNTNG1
Gene Id22854
DomainLaminin_EGF; Laminin_N
Pfam PF00053   PF00055  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.8 Development hsa04360 Axon guidance
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04514 Cell adhesion molecules (CAMs)
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009887 animal organ morphogenesis
Biological Process GO:0007409 axonogenesis
Biological Process GO:0070831 basement membrane assembly
Biological Process GO:0016477 cell migration
Biological Process GO:2001222 regulation of neuron migration
Biological Process GO:0150011 regulation of neuron projection arborization
Biological Process GO:0010975 regulation of neuron projection development
Biological Process GO:0034446 substrate adhesion-dependent cell spreading
Biological Process GO:0099560 synaptic membrane adhesion
Biological Process GO:0009888 tissue development
molecular function GO:0050839 cell adhesion molecule binding
molecular function GO:0098632 cell-cell adhesion mediator activity
cellular component GO:0046658 anchored component of plasma membrane
cellular component GO:0005576 extracellular region
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0043256 laminin complex
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003125 BXGD000179 Anorexia Nervosa Mental Disorders
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005587 BXGD000316 Depression, Bipolar Mental Disorders
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0024433 BXGD001771 Macrostomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0024713 BXGD001799 Manic Disorder Mental Disorders
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0035372 BXGD002544 Rett Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0151611 BXGD003447 Electroencephalogram abnormal Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0200635 BXGD004041 Lymphocyte Count measurement
C0202236 BXGD004086 Triglycerides measurement
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0338831 BXGD007216 Manic Mental Disorders
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0409348 BXGD008384 Flexion contracture of proximal interphalangeal joint
C0423867 BXGD008517 Fine hair
C0424139 BXGD008520 Anxiety and fear
C0426421 BXGD008561 Wide nose
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0454455 BXGD008835 Mirror movements disorder Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598589 BXGD009667 Inherited neuropathies Nervous System Diseases
C0600427 BXGD009706 Cocaine Dependence Chemically-Induced Disorders; Mental Disorders
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1096063 BXGD011600 Drug Resistant Epilepsy Nervous System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1305855 BXGD012348 Body mass index
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1834055 BXGD013953 Underdeveloped nasal alae
C1836543 BXGD014130 Thick vermilion border
C1836830 BXGD014165 Developmental regression Mental Disorders
C1850049 BXGD015101 Clinodactyly of the 5th finger
C1865014 BXGD016282 Long philtrum
C2748910 BXGD017609 Rett Syndrome, Atypical Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C3278923 BXGD018748 Dilated ventricles (finding)
C3279222 BXGD018751 Aplasia/Hypoplasia of the cerebellum
C3496069 BXGD019017 cocaine use
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4021785 BXGD020778 Abnormality of the metacarpal bones Musculoskeletal Diseases
C4024167 BXGD021295 Abnormality of the antitragus
C4282128 BXGD022420 PATENT DUCTUS ARTERIOSUS 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4551583 BXGD023361 Cerebral cortical atrophy
C4553743 BXGD023548 Spasticity, CTCAE
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein