Showing entry for Lambda-crystallin homolog


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022245
Protein NameLambda-crystallin homolog
Uniport IdQ9Y2S2
GeneCRYL1
Gene Id51084
Domain3HCDH; 3HCDH_N
Pfam PF00725   PF02737  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00040 Pentose and glucuronate interconversions
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006631 fatty acid metabolic process
Biological Process GO:0019640 glucuronate catabolic process to xylulose 5-phosphate
molecular function GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
molecular function GO:0050104 L-gulonate 3-dehydrogenase activity
molecular function GO:0070403 NAD+ binding
molecular function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-5661270 Formation of xylulose-5-phosphate
R-HSA-71387 Metabolism of carbohydrates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009691 BXGD000622 Congenital cataract Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Nervous System Diseases
C0010709 BXGD000689 Cyst Pathological Conditions, Signs and Symptoms; Neoplasms
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017536 BXGD001114 Giardiasis Digestive System Diseases; Infections
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020501 BXGD001409 Primary Hyperoxaluria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0086543 BXGD003294 Cataract Eye Diseases
C0154301 BXGD003714 Acquired thrombocytopenia Hemic and Lymphatic Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0275524 BXGD006376 Coinfection Infections
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0343386 BXGD007620 Clostridium difficile infection Infections
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0474808 BXGD008959 Follicular neoplasm Neoplasms
C0520459 BXGD009084 Necrotizing Enterocolitis Digestive System Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0687720 BXGD009844 Central Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1411966 BXGD013047 Clostridium; difficile (disorder)
C1864903 BXGD016270 Hyperinsulinemic hypoglycemia Nutritional and Metabolic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3805278 BXGD019474 Extrahepatic Cholangiocarcinoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein