Showing entry for Guanine deaminase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022246
Protein NameGuanine deaminase
Uniport IdQ9Y2T3
GeneGDA
Gene Id9615
DomainAmidohydro_1
Pfam PF01979  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006147 guanine catabolic process
Biological Process GO:0046098 guanine metabolic process
Biological Process GO:0007399 nervous system development
Biological Process GO:0006139 nucleobase-containing compound metabolic process
Biological Process GO:0006195 purine nucleotide catabolic process
molecular function GO:0019239 deaminase activity
molecular function GO:0008892 guanine deaminase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005829 cytosol
cellular component GO:0005622 intracellular
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-74259 Purine catabolism
R-HSA-8956319 Nucleobase catabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0024667 BXGD001794 Animal Mammary Neoplasms Neoplasms; Animal Diseases
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0205696 BXGD004107 Anaplastic carcinoma Neoplasms
C0205697 BXGD004108 Carcinoma, Spindle-Cell Neoplasms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0205699 BXGD004110 Carcinomatosis Neoplasms
C0410158 BXGD008408 Muscle damage
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C1257925 BXGD011814 Mammary Carcinoma, Animal Neoplasms; Animal Diseases
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001409 7-Methylxanthine 166.14
BXGC0001502 Caffeine 194.19
BXGC0002912 Guanine 151.13
BXGC0003981 2,6-Diaminopurine 150.14
BXGC0008062 Uric acid 168.11
BXGC0038499 Xanthine 152.03
BXGC0039270 4-Amino-1H-Imidazole-5-Carboxamide 126.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein