Showing entry for Mitochondrial fission 1 protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022257
Protein NameMitochondrial fission 1 protein
Uniport IdQ9Y3D6
GeneFIS1
Gene Id51024
DomainFis1_TPR_C; Fis1_TPR_N
Pfam PF14853   PF14852  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0000422 autophagy of mitochondrion
Biological Process GO:0035584 calcium-mediated signaling using intracellular calcium source
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:1901653 cellular response to peptide
Biological Process GO:1904579 cellular response to thapsigargin
Biological Process GO:0097237 cellular response to toxic substance
Biological Process GO:0000266 mitochondrial fission
Biological Process GO:0043653 mitochondrial fragmentation involved in apoptotic process
Biological Process GO:0008053 mitochondrial fusion
Biological Process GO:0070584 mitochondrion morphogenesis
Biological Process GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration
Biological Process GO:0016559 peroxisome fission
Biological Process GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Biological Process GO:0051561 positive regulation of mitochondrial calcium ion concentration
Biological Process GO:0090141 positive regulation of mitochondrial fission
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:0090314 positive regulation of protein targeting to membrane
Biological Process GO:0006626 protein targeting to mitochondrion
Biological Process GO:0010821 regulation of mitochondrion organization
Biological Process GO:0001836 release of cytochrome c from mitochondria
Biological Process GO:1905395 response to flavonoid
Biological Process GO:1902617 response to fluoride
Biological Process GO:1990910 response to hypobaric hypoxia
Biological Process GO:0014850 response to muscle activity
Biological Process GO:0031667 response to nutrient levels
molecular function GO:0042802 identical protein binding
molecular function GO:0044877 protein-containing complex binding
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0031307 integral component of mitochondrial outer membrane
cellular component GO:0005779 integral component of peroxisomal membrane
cellular component GO:0016020 membrane
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0005777 peroxisome
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
R-HSA-9603798 Class I peroxisomal membrane protein import
R-HSA-9609507 Protein localization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015696 BXGD001014 Fatty Liver, Alcoholic Digestive System Diseases; Chemically-Induced Disorders
C0017638 BXGD001132 Glioma Neoplasms
C0017665 BXGD001141 Membranous glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021655 BXGD001508 Insulin Resistance Nutritional and Metabolic Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0026618 BXGD001909 Dental Fluorosis, Acquired Stomatognathic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0035455 BXGD002554 Rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0037926 BXGD002712 Compression of spinal cord Nervous System Diseases; Wounds and Injuries
C0153349 BXGD003621 Malignant neoplasm of tongue Neoplasms; Stomatognathic Diseases
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0273115 BXGD006366 Lung Injury Respiratory Tract Diseases; Wounds and Injuries
C0338508 BXGD007196 Optic Atrophy 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0340100 BXGD007304 High altitude pulmonary edema Respiratory Tract Diseases
C0349566 BXGD007928 Squamous cell carcinoma of tongue Neoplasms; Stomatognathic Diseases
C0558353 BXGD009451 Tongue Carcinoma Neoplasms; Stomatognathic Diseases
C0600519 BXGD009712 Ventricular Remodeling Pathological Conditions, Signs and Symptoms
C0600520 BXGD009713 Left Ventricle Remodeling Pathological Conditions, Signs and Symptoms
C0872084 BXGD011319 Sarcopenia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C2609414 BXGD017182 Acute kidney injury Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2931673 BXGD018046 Ceroid lipofuscinosis, neuronal 1, infantile Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3839868 BXGD019788 Cytogenetically normal acute myeloid leukemia Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein