Showing entry for SH3 domain-binding protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022261
Protein NameSH3 domain-binding protein 1
Uniport IdQ9Y3L3
GeneSH3BP1
Gene Id23616
DomainBAR; RhoGAP
Pfam PF03114   PF00620  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007015 actin filament organization
Biological Process GO:0034329 cell junction assembly
Biological Process GO:0016477 cell migration
Biological Process GO:0045198 establishment of epithelial cell apical/basal polarity
Biological Process GO:0051058 negative regulation of small GTPase mediated signal transduction
Biological Process GO:0006911 phagocytosis, engulfment
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0030834 regulation of actin filament depolymerization
Biological Process GO:0043535 regulation of blood vessel endothelial cell migration
Biological Process GO:0035020 regulation of Rac protein signal transduction
Biological Process GO:0071526 semaphorin-plexin signaling pathway
molecular function GO:0005096 GTPase activator activity
molecular function GO:0048365 Rac GTPase binding
molecular function GO:0030215 semaphorin receptor binding
molecular function GO:0017124 SH3 domain binding
cellular component GO:0005912 adherens junction
cellular component GO:0005923 bicellular tight junction
cellular component GO:0031252 cell leading edge
cellular component GO:0005829 cytosol
cellular component GO:0030027 lamellipodium
cellular component GO:0005634 nucleus
cellular component GO:0001891 phagocytic cup
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004275 Acetaldehyde 44.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein